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KMID : 0352419920110030439
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Keimyung Medical Journal
1992 Volume.11 No. 3 p.439 ~ p.445
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Clinical Study of Tsutsugamushi disease Occurred in The Daegu, Kyungpook Province
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박정모
손소호/이준호/김윤년/윤덕구/양창헌
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Abstract
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Tsutsugamushi disease is acute febrile illness primarily affecting farmer and prevalent in Autumn. The disease is characterized by fever, rash and eschar and sometimes it caused atypical pneumonitis and it should be differentiated by
Leptospirosis
and
Korean hemorrhagic fever. We experienced 38 cases of Tsutasugamushi disease diagnosed by clinical and detection of tsutsugamushi antibody by indirect immunofluorescent technique.
Studied subjects were 15 cases of male and 23 cases of female and the victim were primarily farmer(89%). Most cases were occured in October and september and in 1990. Fever and chills(94%) were the most complaint symptoms and other complaint
symptoms
were myalgia cough and dyspnea in the order of frequency. Leukocytosis or leukopenia was detected in 14% and 11% respectively and 83% were detected to have thrombocytopenia. Transaminase was elevated in 57% and BUN and creatinine was elevated in
3%.
Physical examination showed eschar(84%). Rash(82%) hypatosplenomegaly(24%). Conjunctival injection and hyperemia of pharynx. chest Xray showed interstitial pneumonitis (11%) pulmonary edema(11%) cardiomegaly(8%). 57% were revealed positive
reaction
to
indirect fluorescent antibody technique. Clinical response was very good in the treatment of tetracycline, vibramycin, or chloramphenicol.
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KEYWORD
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